Search results for "Fibrohistiocytic tumor"

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Congenital dermatofibrosarcoma protuberans: 30 years of follow-up

2007

Summary Dermatofibrosarcoma protuberans (DFSP) is a rare fibrohistiocytic tumor that commonly appears in adult patients. Few cases of DFSP in childhood have been reported. We describe a case of congenital DFSP that had been incompletely excised in childhood, and again at 28 years of age. The 33-year-old woman presented with a recurrence. When comparing the histologic features of the previous specimens excised in 1970 and 30 years later, the similar typical storiform pattern of fibromatous cells was found. The small number of proliferation-marker-positive cells was not altered over the course of 30 years. In line with a few additional reports, we suggest that congenital dermatofibrosarcoma p…

Adultmedicine.medical_specialtySkin NeoplasmsAdult patientsbusiness.industryDermatofibrosarcomaDermatologyFibrohistiocytic tumormedicine.diseaseDermatologyChild PreschoolDermatofibrosarcoma protuberansmedicineHumansFemaleNeoplasm Recurrence LocalbusinessFollow-Up StudiesJDDG
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Nonepithelial skin tumors with multinucleated giant cells

2013

Recognition of the different types of multinucleated giant cells in neoplastic and pseudotumoral lesions of the skin may be helpful in the differential diagnosis of these tumors. In this review, we will analyze the different types of multinucleated giant cells that can be found in nonepithelial cutaneous tumors and, more importantly, the clinicopathological context in which they are found. Touton giant cells are typically present in juvenile xanthogranuloma, necrobiotic xanthogranuloma, and some subtypes of xanthomas. Giant cells with a ground glass appearance are typically present in the solitary reticulohistiocytoma and multicentric reticulohistiocytosis. Osteoclast-like cells are found i…

Pathologymedicine.medical_specialtySkin NeoplasmsHistiocytosis Non-Langerhans-CellJuvenile xanthogranulomaSoft Tissue NeoplasmsFibromaBiologyGiant CellsPathology and Forensic MedicineTouton giant cellXanthomatosismedicineHumansGiant Cell TumorsNecrobiotic xanthogranulomaHistiocytoma Benign FibrousPlexiform fibrohistiocytic tumorDermatofibrosarcomaGiant Cell TumorsAtypical fibroxanthomamedicine.diseaseGiant cellLipomaPleomorphic lipomaXanthogranuloma JuvenileSeminars in Diagnostic Pathology
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